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The new scientific review does not reveal the clinical significance of supplements for weight loss. Chris Rogers / Getty Images:
  • Researchers conducted a systematic review of randomized controlled trials on the choice of weight loss supplements and alternative therapies.
  • They did not find any quality evidence of the effectiveness of any of the reviewed products.
  • The accompanying opinion calls for a more detailed study of the additive industry և its role in promoting “misleading claims” on products.
  • The Food Safety Board, which represents the supplement industry, has questioned the validity of this latest study.

Adults in the United States trying to maintain a moderate weight about a third They say they used supplements to achieve their goal.

However, according to a new review, there is currently no evidence of the usefulness of many weight loss products and alternative therapies.

A systematic review of randomized controlled trials, the gold standard for clinical trials, appears in the journal Obesity:,

“Our findings are important for physicians, researchers, and industry, as they suggest the need for a rigorous evaluation of weight loss products,” said author Cha on Batsis, a physician at Chapel Hill University School of Medicine in North Carolina.

“Only then can we produce data that enables physicians to provide a higher degree of approval for investment and counseling for our patients,” he added.

In: Prevalence of obesity Adult growth in the United States has continued in recent years, from 33.7% in 2007-2008 to 39.6% in 2015-2016.

The condition is associated with an increased risk of diabetes, heart disease, cancer and premature death.

People often struggle to lose weight; Եւ Food or Drug Administration (FDA) approved treatment or lack of efficacy, or inaccessibility to health care professionals who may provide antiseptic therapy.

Researchers write that many people take over-the-counter weight loss supplements believing that they are “natural” or “clinically proven”. Consumers may even believe that these products are as safe as FDA-approved drugs.

In addition, scientists say that health professionals have little information about the scientific claims made by the promoters of such therapies.

The researchers looked at randomized controlled trials evaluating the effectiveness of 14 supplements, therapies, or two, including:

  • Acupuncture
  • green tea
  • ephedra or caffeine
  • guar gum
  • chitosan
  • Calcium-Vitamin D Supplements
  • chocolate or cocoa
  • chrome
  • pyruvate:
  • mind-body therapies

Out of a total of 315 trials, they rated 52 as low risk of bias – for example, sufficient data to support any assertion of their design or reporting imperfections or effectiveness.

Sixteen of them reported a statistically significant weight loss throughout the period, ranging from 0.3 to 4.93 kilograms.

However, the authors write that these reductions “had no clinical significance.”

“The result can be statistically significant without having clinical significance,” said prof. The gap Medical news today,

He said that clinical guidelines consider weight loss of more than 5% to be of clinical significance.

“During our study of additional studies, in the rare cases where people lost weight, they did not lose enough weight to have a positive effect on their health,” he said.

In their article, the researchers conclude:

“Although there have been a number of studies evaluating dietary supplements and alternative therapies for weight loss, this review does not support any strong, high-quality evidence of product effectiveness.”

1994 Law on Health և Dietary Supplements Education weakened regulation in the dietary supplement industry.

By law, The FDA does not regulate supplements in the same way as prescription anti-obesity drugs. However, while manufacturers cannot claim that their products can cure, cure or prevent any disease, they do have to provide evidence of their safety.

In: Dietary Supplements Office publishes documents on these products, maintains a database of their components, labels.

Strictly formulated piece of opinion The members of the clinical committee of the prostitution company note that the annual sales of weight loss supplements amount to $ 30 billion, despite the “substantial evidence”.

The authors urge regulators to “critically examine the food supplement industry, including their role in promoting misleading claims and marketing products that have the potential to harm patients.”

Supplementary Nutrition Board (CRN) Chairman և CEO ներկայաց CEO Steve Mister challenged the validity of the study. CRN is “a leading trade union representing nutritional supplements, functional food manufacturers, component suppliers.”

In the provided announcement MNT:, he questioned the inclusion of acupuncture, mind-body interventions, and chocolate, among other things, in the therapies he described as “herbal” products.

He added that manufacturers do not sell vitamin D համար calcium for weight loss.

“There are many safe, healthy weight management supplements on the market that have research support in this category, as well as supplements that help fill the nutrition gaps for consumers who do not get all the nutrients they need from food alone, especially when they are calorie restricted. : or doing strenuous exercise, ”he said.

“The recent review covers only a few components in this area; it should not diminish the supporting role that these products play in consumer weight management programs,” he added.

However, he agreed with the call for more research, adding that industry and academia should strengthen their research collaboration.