This week’s summary of recent research on coronavirus և treatment երը efforts to find vaccines suggest that cases of asymptomatic COVID-19 are very common in patients, weight loss surgery may be associated with better disease outcomes, smoking may be reduced immune response. Persistent respiratory problems in cases of mRNA stroke և “prolonged COVID-19” may be due to microscopic damage to the lungs.

Asymptomatic COVID-19 is very common

About one-third of people with COVID-19 have no symptoms, according to a review of more than 350 studies published in April 2021.

Asymptomatic infections were more common in children than in the elderly or people who did not already have a medical history. “His team estimates that 46.7% of infected children have no symptoms,” he said.

“This is particularly troubling, as large, well-interacting settings between large groups of young individuals are particularly susceptible to COVID-19 high-speed events that may go undetected if the school authorities only address the symptoms.”

Senior author Alison Galvani, also from Yale School of Public Health, noted that asymptomatic individuals can still transmit the virus to others, which makes wearing masks during the reopening of potential schools.

Weight loss surgery is associated with better results

New obstetric surgery may have a protective effect against the poor results of COVID-19, according to data from a New York hospital.

There, doctors studied 620 patients with COVID-19, including 130 who had previously undergone so-called bariatric surgery to treat their obesity, և 496 patients of the same-sex գիր obese patients but did not undergo surgery. them

Patients who underwent bariatric procedures, such as gastric bypass grafts, gastric lavage, or gastrectomy, were less likely to be hospitalized, less likely to need a mechanical ventilator to breathe, and less likely to die in hospital. , although many of them were still obese.

They were also discharged faster from the hospital, and those who were admitted to the intensive care unit spent fewer days there.

“Patients with obesity have been disproportionately affected by COVID-19, with a higher risk of serious illness and death,” the authors note.

They added that although the study could not prove that bariatric surgery had produced better results, the results showed that it could be a “protective factor against severe COVID-19 …

Sm smart may disrupt the mRNA vaccine response

Current aponomic researchers claim that current smokers may have lower immune responses to COVID-19 vaccines, or that more research is needed.

In a preliminary study of 378 health workers aged 328 to 54, researchers analyzed the level of protective antibodies produced by the mfNA vaccine from Pfizer և BioNTech, using blood samples about three months after the second dose.

Previous studies have shown that older participants had lower levels of antibodies.

The only risk factors for lowering antibody levels with age were male smoking, The difference between the sexes may have been due to the fact that women smoked twice as much as researchers.

In a confirmed article on medRxiv on Saturday, they noted that antibody levels were higher in former smokers than in current smokers, which “suggests that quitting smoking will reduce the risk of lower antibody titers.”

Microscopic damage to the lungs can continue in “prolonged COVID”

Persistent breathing problems that plague some COVID-19 survivors, known as “long-term COVID-19,” may be due to microscopic processes that continue to damage the lungs even after an acute infection.

The researchers examined the blood and respiratory cells of 38 patients who still had respiratory problems at least three months after discharge from the hospital.

Compared to healthy volunteers, the survivors of these COVID-19 survivors had higher numbers of immune cells that protect against viruses but can also cause damage. They had higher levels of protein, which is present during cell death and tissue repair.

The findings, which still need to be confirmed in larger studies, suggest that some patients continue to have immune cell disorders, damage to cells in the airway wall, even a few months after the initial infection and discharge from the hospital. Co-author of the report published in medRxiv before the equation.

“In a small group of patients, we were able to show that the deviations could actually be resolved over time,” Harker said.

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